The danger of high blood sugur

Diabetes, is a group of metabolic diseases in which a person has high blood sugar.

Diabetes is due to either the pancreas not produce enough insulin, or because cells of the body do not respond properly to the insulin that is produced. There are three main types of diabetes mellitus:

1. Type 1 DM results from the body's failure to produce insulin.

2. Type 2 DM results from insulin resistance, a condition in which cells fail to use insulin properly, sometimes also with an absolute insulin deficiency.

Consumption of sugar-sweetened drinks in excess is associated with an increased risk. The type of fats in the diet are also important, with saturated fats and trans fatty acids increasing the risk, and polyunsaturated and monounsaturated fat decreasing the risk. Eating lots of white rice appears to also play a role in increasing risk. A lack of exercise is believed to cause 7% of cases.

Why are high blood sugar levels bad for you? Glucose is precious fuel for all the cells in your body -- when it's present at normal levels. But persistently high sugar levels behave like a slow-acting poison.

High sugar levels slowly erode the ability of cells in the pancreas to make insulin. The pancreas overcompensates, though, and insulin levels remain overly high. Gradually, the pancreas is permanently damaged.

All the excess sugar is modified in the blood. The elevated sugar in the blood causes changes that lead to atherosclerosis, a hardening of the blood vessels.

Because high sugar levels are everywhere, the body can be damaged anywhere. Damage to blood vessels, in particular, means no area is safe from too much sugar. High sugar levels and damaged blood vessels cause the multitude of complications that can come with diabetes

3. Gestational diabetes, is the third main form and occurs when pregnant women without a previous diagnosis of diabetes develop a high blood glucose level.

Artificial sweetener increases the likelihood of gaining weight

Experiments have found that sweet taste, regardless of its caloric content, enhances your appetite. Aspartame has been found to have the most pronounced effect, but the same applies for other artificial sweeteners, such as acesulfame potassium and saccharin.

The reason why glucose or sucrose (table sugar) tends to lead to lower food consumption compared to non-caloric artificial sweeteners is because the calories contained in natural sweeteners trigger biological responses to keep your overall energy consumption constant. This was again evidenced in a study

In essence, real sugar allows your body to accurately determine that it has received enough calories, thereby activating satiety signaling. Without the calories, your appetite is activated by the sweet taste, but as your body keeps waiting for the calories to come, sensations of hunger remain.

http://articles.mercola.com/sites/articles/archive/2012/12/04/saccharin-aspartame-dangers.aspx#!

The Key for a Good Experimental Paper

Have a strong alternative hypothesis. Write about this alternative hypothesis in the introduction. An experimental design is interesting only when multiple outcomes can happen. Get the readers interested in the multiple outcomes.

Irwin–Hall distribution

In probability and statistics, the Irwin–Hall distribution, named after Joseph Oscar Irwin and Philip Hall, is probability distribution for a random variable defined as sum of a number of independent random variables, each having a uniform distribution.[1] For this reason it is also known as the uniform sum distribution.

What statistical analysis should I use?

Number of Dependent Variables	Nature of Independent Variables	Nature of Dependent Variable(s)	Test(s)
1	0 IVs (1 population)	interval & normal	one-sample t-test	Stata
		ordinal or interval	one-sample median	Stata
		categorical  (2 categories)	binomial test	Stata
		categorical	Chi-square goodness-of-fit	Stata
	1 IV with 2 levels (independent groups)	interval & normal	2 independent sample t-test	Stata
		ordinal or interval
			Wilcoxon-Mann Whitney test	Stata
		categorical	Chi- square test	Stata
			Fisher's exact test	Stata
	1 IV with 2 or more levels (independent groups)	interval & normal	one-way ANOVA	Stata
		ordinal or interval	Kruskal Wallis	Stata
		categorical	Chi- square test	Stata
	1 IV with 2 levels (dependent/matched groups)	interval & normal	paired t-test	Stata
		ordinal or interval	Wilcoxon signed ranks test	Stata
		categorical	McNemar	Stata
	1 IV with 2 or more levels (dependent/matched groups)	interval & normal	one-way repeated measures ANOVA	Stata
		ordinal or interval	Friedman test	Stata
		categorical	repeated measures logistic regression	Stata
	2 or more IVs (independent groups)	interval & normal	factorial ANOVA	Stata
		ordinal or interval	ordered logistic regression	Stata
		categorical	factorial logistic regression	Stata
	1 interval IV	interval & normal	correlation	Stata
			simple linear regression	Stata
		ordinal or interval	non-parametric correlation	Stata
		categorical	simple logistic regression	Stata
	1 or more interval IVs and/or 1 or more categorical IVs	interval & normal	multiple regression	Stata
			analysis of covariance	Stata
		categorical	multiple logistic regression	Stata
			discriminant analysis	Stata
2 or more	1 IV with 2 or more levels (independent groups)	interval & normal	one-way MANOVA	Stata
2 or more	2 or more	interval & normal	multivariate multiple linear regression	Stata
2 sets of 2 or more	0	interval & normal	canonical correlation	Stata
2 or more	0	interval & normal	factor analysis	Stata
Number of Dependent Variables	Nature of Independent Variables	Nature of Dependent Variable(s)	Test(s)

Source: http://www.ats.ucla.edu/stat/stata/whatstat/
http://www.ats.ucla.edu/stat/stata/whatstat/whatstat.htm#1sampt


In statistics, Spearman's rank correlation coefficient or Spearman's rho, named after Charles Spearman and often denoted by the Greek letter  (rho) or as , is a nonparametric measure of statistical dependence between two variables. It assesses how well the relationship between two variables can be described using a monotonic function. If there are no repeated data values, a perfect Spearman correlation of +1 or −1 occurs when each of the variables is a perfect monotone function of the other.

Risk vs Uncertainty

Risk applies to situations where we do not know the outcome of a given situation, but can accurately measure the odds. Uncertainty, on the other hand, applies to situations where we cannot know all the information we need in order to set accurate odds in the first place.

Evolution of preferences

McDermott, Folwer, and Smirnov (Journal of Politics, 2008): Evolutionary origin of prospect theory. Basic assumption: in some period, an individual must acquire a minimum threshold tau of food in order to live to the next period. Using optimal foraging theory, they show that context-dependent risk aversion and risk-seeking behavior have their evolutionary advantage when the probability of survival depends on the amount of food epsilon an individual acquires from the environment: Pr(epsilon > tau.)


Sozou (The Royal Society, 1998): On hyperbolic discounting and uncertain hazard rates. Basic assumption: there is a risk that the reward will not be realized. For constant hazard rate, exponential time-preferences follow. When there is uncertainty in the underlying hazard rate, hyperbolic discounting can be derived given certain given exponential prior distribution of the hazard rate.